Making Mice: Standardizing Animals for American Biomedical Research, 1900-1955
| Author | : | |
| Rating | : | 4.24 (558 Votes) |
| Asin | : | 0691016364 |
| Format Type | : | paperback |
| Number of Pages | : | 312 Pages |
| Publish Date | : | 2013-02-15 |
| Language | : | English |
DESCRIPTION:
C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. It will appeal not only to historians
"The story of the defined laboratory mouse" according to J. Rygaard. This book describes in vivid detail the development of defined laboratory mice, centered at the Jackson Laboratory, Bar Harbor, Maine. As a user of defined mouse strains for nearly forty years I have enjoyed reading the book and have recommended it to younger colleagues. In my teaching I have often stressed the importance of knowledge of the background on which we are working in (experimental) biomedicine. Karen Rader's book is a rich source to the recent history of medicine.
And as time passed, distribution problems were exacerbated by an increasing concern about preventing infectious agents from spreading between colonies. . For the historian of science, one remaining question concerns the extent to which our present policymakers were able to draw on the lessons of the past in addressing these current issues and the extent to which they reinvented solutions to past problems. (Figure) For Rader, this story became a case history for evaluating the effects that social factors have had on research processes and necessities. It is also very much the story of one man and one institution. The man was Clarence Cook "Prexy" Little, who initiated the development of inbred mice in 1909 while working as an undergraduate at Harvard's Bussey Institution. All rights reserved. Rader's expressed g